Opisthorchis sinensis
Chinese liver fluke
https://www.flickr.com/photos/lunarcaustic/2246777715/
Physiology and Structure
- Its lifecycle involves 2 intermediate hosts.
- It differs from other fluke cycles.
- Its hosts would mainly be freshwater fish.
- Upon consumption, flukes develop first in the duodenum and migrate to the bile ducts where they become adults.
- They are able to live in the binary tract for up to 50 years and produce approximately 2000 eggs per day.
Life cycle
https://www.fao.org/docrep/008/y5970e/y5970e04.jpg
Clinical Syndromes
- Infection in humans is usually mild and asymptomatic.
- Severe infection with many flukes in the bile duct would lead to fever, diarrhea, epigastric pain, hepatomegaly, anorexia and occasionally jaundice.
- Biliary obstruction, chronic infection may occur.
Treatment, Prevention and Control
- Prevention of infection is done by not consuming uncooked fish, having proper sanitation and the proper disposal of feces.